The science behind this may well be plausible - that cures for human ailments may well rest elsewhere in the animal kingdom. To that end Saffron Burrows ("Susan") enlists the help of millionaire philanthropist "Russell Franklin" (Samuel L. Jackson) to develop a cure for Alzheimer's using sharks captive in a converted offshore submarine refuelling base. When he arrives at the facility he meets the rather oddball crew including "Carter" (Thomas Jane") "Preacher" (LL Cool J) and "Jim" (Stellan Skarsgård) before quickly discovering that these genetically altered fish are tired of being the guinea-pigs in the lab and are bent on revenge. The film does not hang about; the effects are quite scary at times but the one great snag is given that the sharks are supposed to be super-intelligent: why did they agree to star in a film with the dreadfully flat Burrows - there are bits of flotsam in this film less wooden than her performance. Jane & LL Cool J have some fun as they try to evade their menacing foes and though it certainly isn't "Jaws"; it's not terrible...